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Synthesis, purification and conformational studies on enkephalin derivatives containing gamma-amino-n-butyric acid
International Journal of Peptide and Protein Research
|November 1, 1982
Abstract:
The solid-phase synthesis of several analogs of enkephalin containing gamma-amino-butyric acid is reported. Synthetic strategies, purification methods, chemical and physicochemical characterization are discussed. The n.m.r. data suggest for some of the analogs structural features similar to the opioids.