Related Experiment Video

Updated: Aug 3, 2026

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

Comparing the mydriatic effect of tropicamide with respect to iris pigmentation

R W Richardson

    Journal of the American Optometric Association
    |November 1, 1982
    PubMed

    It has been believed over the years that mydriatics have had lesser effect on darker pigmented irides. In this study pupillary diameter was measured under 70 foot-candles of illumination before and after 1% tropicamide was instilled for a duration period of 30 minutes. It was concluded that, (a) 1% tropicamide did dilate the pupil, (b) light irides were significantly larger than dark irides before dilation, (c) no significant difference in the change of pupil size between light and dark irides was evidenced.

    More Related Videos

    Using Retinal Imaging to Study Dementia09:17

    Using Retinal Imaging to Study Dementia

    Published on: November 6, 2017

    Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats06:30

    Ocular Therapeutic Delivery and Advanced Tissue Retrieval in Adult Rats

    Published on: May 23, 2025

    Related Concept Videos

    Open Angle Glaucoma: Treatment01:27

    Open Angle Glaucoma: Treatment

    In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
    Drugs such as carbonic anhydrase inhibitors, α2- and...
    Ophthalmic Drug Delivery Systems01:23

    Ophthalmic Drug Delivery Systems

    Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...