Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Collagen in the human placenta]

H Hirayama, T Okuyama, H Furuya

    Nihon Sanka Fujinka Gakkai Zasshi
    |November 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Collagen content and activity increase throughout human pregnancy, indicating its crucial role in placental development. Prolyl hydroxylase activity is highest in the first trimester, supporting collagen synthesis during early placental formation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Detection of Phomopsis sclerotioides in Commercial Cucurbit Field Soil by Nested Time-Release PCR.

    Plant disease·2019
    Same author

    Disseminated toxoplasmosis with atypical symptoms which developed with exacerbation of systemic lupus erythematosus.

    Lupus·2018
    Same author

    How to improve the endoscopic view of the hypopharynx: Validation of our novel modified Killian's Method to expose the hypopharynx in 20 subjects.

    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·2018
    Same author

    Development of the Infusoriform Embryo of Dicyema japonicum (Mesozoa: Dicyemidae).

    The Biological bulletin·2018
    Same author

    Effects of diazepam and flumazenil on forebrain ischaemia in a rat model of benzodiazepine tolerance.

    British journal of anaesthesia·2012
    Same author

    Characterization of a new Anulavirus isolated from Amazon lily plants.

    Archives of virology·2012
    Same journal

    [A case of fibrosarcoma of the ovary].

    Nihon Sanka Fujinka Gakkai zasshi·1996
    Same journal

    [Ovarian cancer with prior gynecological laparotomy].

    Nihon Sanka Fujinka Gakkai zasshi·1996
    Same journal

    [Clinical and histopathologic features of the uterine lipoleiomyoma].

    Nihon Sanka Fujinka Gakkai zasshi·1996
    Same journal

    [A case of peritonitis with systemic lupus erythematosus].

    Nihon Sanka Fujinka Gakkai zasshi·1996
    Same journal

    Attempt to continue pregnancy of remaining fetuses after delivery of preceding fetus in multiple pregnancies before 24 weeks gestation: report of three cases.

    Nihon Sanka Fujinka Gakkai zasshi·1996
    Same journal

    [Findings of uterine sarcoma and uterine myoma by color and power Doppler].

    Nihon Sanka Fujinka Gakkai zasshi·1996
    See all related articles

    Area of Science:

    • Biochemistry
    • Obstetrics
    • Developmental Biology

    Context:

    • The human placenta undergoes significant structural and functional changes during pregnancy.
    • Collagen is a key structural protein essential for tissue development and integrity.
    • Understanding collagen's role is vital for assessing placental health and fetal development.

    Purpose:

    • To investigate the quantitative and qualitative changes in placental collagen during pregnancy.
    • To measure hydroxyproline content, collagen solubility, and prolyl hydroxylase activity.
    • To elucidate the role of collagen in placental development and construction.

    Summary:

    • Hydroxyproline content significantly increases from the first to the third trimester (0.41 to 2.17 mg/g wet weight).

    Related Experiment Videos

  • Collagen solubility shows a proportional increase in the pepsin-soluble fraction and a decrease in the insoluble fraction.
  • Prolyl hydroxylase activity is markedly higher in the first trimester (1058.5 C.P.M./mg protein) compared to later stages.

    • Impact:

    • Findings suggest collagen plays a critical role in the developmental construction of the human placenta.
    • Changes in collagen content, nature, and synthesis enzymes correlate with gestational progression.
    • This research provides insights into the biochemical basis of placental growth and maturation.