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Published on: October 17, 2018
[Hypoglycorrhachia in mumps meningitis (author's transl)]
Abstract:
Eighty cases of mumps meningitis are studied in children between the ages of one to seven years. The parotids were affected before, after and during the meningitis in all cases. In fifteen cases, when admitted to the hospital, levels of glucose were found in the C.S.F. equal or lower than 40 mg/100 ml. In three of them the hypoglycorrhachia persisted for a long time, as reported by other authors. The possible causes of low C.S.F. glucose values in meningitis are analized, not explanation for this phenomenon in viral meningitis is found.
Insights
This study on mumps meningitis in children found low cerebrospinal fluid (CSF) glucose levels in 15% of cases. The exact cause of this hypoglycorrhachia in viral meningitis remains unexplained.
Area of Science:
- Pediatrics
- Infectious Diseases
- Neurology
Context:
- Mumps meningitis is a common viral infection affecting children.
- Parotid gland involvement is a consistent clinical feature.
- Cerebrospinal fluid (CSF) glucose levels can be affected during meningitis.
Purpose:
- To investigate the occurrence and characteristics of low CSF glucose in pediatric mumps meningitis.
- To analyze potential causes for hypoglycorrhachia in viral meningitis.
Summary:
- Eighty children aged 1-7 years with mumps meningitis were studied.
- Fifteen cases (18.75%) presented with low CSF glucose levels (≤40 mg/100 ml).
- Hypoglycorrhachia persisted long-term in three patients, aligning with previous reports, but a definitive cause in viral meningitis was not identified.
Impact:
- Highlights a potential complication of mumps meningitis in children.
- Underscores the need for further research into the mechanisms of CSF glucose dysregulation in viral infections.
- Informs clinical awareness regarding CSF glucose monitoring in pediatric meningitis cases.
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