[Clinico-biochemical correlates in adolescents with abnormal rates of psychophysical development]

The authors examined 106 adolescents with behaviour anomalies treated at Daytime Psychotherapeutic Ward of Moscow Children's Psychiatric Hospital No. 6. In 96 of them, borderline neuropsychic disturbances and in 10 schizophrenia were diagnosed. A correlation between the clinical signs of the personality dysharmonic formation and the lipid composition of the blood plasma was revealed. It is shown that all the adolescents with the anomalous behaviour have hyperlipidemia with prevalence of the processes of lipolysis in patients with signs of acceleration, and of lipid synthesis in patients with retardation. In the schizophrenic patients a deficit of phospholipids and alpha-lipoproteids was observed. All the patients showed hypercholesterolemia, which, however, had certain peculiarities in each group. The lipid metabolism disorders revealed may be a cause of an intensification of psychomotor activity that may lead in a certain socio-psychological environment to behaviour anomalies of delinquent character.