Related Experiment Video
Updated: Aug 10, 2026

In Vivo Electrophysiological Measurements on Mouse Sciatic Nerves
Published on: April 13, 2014
Sensory and motor maximum nerve conduction velocity in the peripheral and central nervous system of the beagle dog
Abstract:
Sensory maximum nerve conduction velocity (MNCV) and motor MNCV were monitored in altogether 14 beagle dogs anaesthetized with pentobarbital. Sensory MNCV was determined by averaging cortically evoked potentials from somatosensory area I (SS I) in response to repeated electrical stimulation of digital paw pads, tibial nerve at calcaneus or sciatic nerve at trochanter. Sensory MNCV determined from paw to tibial nerve at calcaneus was 53 m/sec, from tibial nerve at calcaneus to sciatic nerve at trochanter 64 m/sec and from sciatic nerve at trochanter to crotex SS I 53 m/sec. Motor peripheral MNCV determined in the customary way from sciatic nerve at trochanter to tibial nerve at calcaneus was 68 m/sec and distal latency 3.6 msec. Motor central MNCV from motor cortex to the sciatic nerve at the trochanter in 5 unanaesthetized dogs was 57 m/sec. These testing procedures serve for quantitative assessment of possible impairment of impulse transmission in the central and peripheral sensory and motor pathway of beagle dogs used in routine toxicity studies.
More Related Videos
06:35In Vivo Electrophysiological Measurement of Compound Muscle Action Potential from the Forelimbs in Mouse Models of Motor Neuron Degeneration
Published on: June 15, 2018
07:12Assessment of Sensory Thresholds in Dogs Using Mechanical and Hot Thermal Quantitative Sensory Testing
Published on: October 26, 2021
Related Concept Videos
Action Potentials
Action Potential
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Nervous Tissue: Myelin
Schwann cells begin to form myelin sheaths around axons during fetal development. They wrap around a small...
Action Potential
Membrane potential in neurons
Neurons typically have a resting membrane potential of about -70 millivolts (mV). When they receive...
Spinal Cord: Information Processing
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Major Somatic Sensory Pathways