Pulmonary and disseminated Mycobacterium simiae infection in humans
Abstract:
Three patients with Mycobacterium simiae infection were seen during a 5-yr period. One patient with chronic infiltrative pulmonary disease had the diagnosis established by open lung biopsy. Two patients with normal chest roentgenograms had disseminated infection, one having had elective surgery for a nonfunctioning kidney. Caseating granulomata were discovered in kidney tissue sections. Both M. kansasii and M. simiae were subsequently recovered from bone marrow and urine cultures. The other patient had vertebral osteomyelitis, and M. simiae was isolated from tissue obtained by needle biopsy. To our knowledge, disseminated M. simiae infection has not been previously described.
Related Concept Videos
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Atypical Pneumonia
Tuberculosis


