Related Experiment Video
Updated: Aug 12, 2026

The Use of the Ex Vivo Chandler Loop Apparatus to Assess the Biocompatibility of Modified Polymeric Blood Conduits
Published on: August 20, 2014
Severe reactions to Cuprophan capillary dialyzers
Abstract:
Five severe reactions occurred in four maintenance hemodialysis patients 1 to 5 minutes after initiating dialysis with Cuprophan capillary dialyzers. All reactions were life-threatening and one resulted in death. Inadequate rinsing of the dialyzers was probably the cause of the reactions. The severe reactions were managed by immediate discontinuation of dialysis and the institution of supportive treatment. Antianaphylactic measures were also attempted, but their therapeutic effectiveness remains to be determined.
More Related Videos
Related Concept Videos
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy
Drug Toxicity: Allergic Reactions
Allergic Reactions: Anaphylaxis
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Hemodialysis II: Procedure and Complications

