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Eosinophilic peritonitis

B S Spinowitz, R A Golden, J H Rascoff

    Clinical and Experimental Dialysis and Apheresis
    |January 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Cloudy peritoneal dialysis fluid does not always indicate bacterial infection. This study identifies eosinophilic peritonitis as a cause of cloudy effluent, distinct from bacterial peritonitis in Continuous Ambulatory Peritoneal Dialysis patients.

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    Area of Science:

    • Nephrology
    • Internal Medicine
    • Clinical Diagnostics

    Background:

    • Cloudy peritoneal dialysis effluent is a common concern for patients undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD).
    • Distinguishing the cause of cloudy effluent is crucial for appropriate patient management.
    • Bacterial peritonitis is the most frequent cause, but other conditions can present similarly.

    Purpose of the Study:

    • To investigate non-bacterial causes of cloudy peritoneal dialysis effluent.
    • To describe the clinical presentation and diagnostic features of eosinophilic peritonitis.
    • To differentiate eosinophilic peritonitis from bacterial peritonitis.

    Main Methods:

    • Analysis of peritoneal dialysis effluent from eight patients presenting with cloudy fluid.

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  • Microbiological culture of dialysate to rule out bacterial growth.
  • Cell count analysis of dialysate to identify specific cell types, particularly eosinophils.

    • Main Results:

    • Dialysate cultures were negative for bacterial growth in all eight patients.
    • Peritoneal fluid analysis revealed significant eosinophil counts in these patients.
    • This presentation is characteristic of eosinophilic peritonitis.

    Conclusions:

    • Cloudy peritoneal dialysis effluent can be caused by eosinophilic peritonitis, not solely bacterial infection.
    • Eosinophilic peritonitis has distinct clinical and laboratory features.
    • Identifying eosinophilic peritonitis avoids unnecessary antibiotic treatment for bacterial infection.