Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Disorders of kidney function in hepatic coma]

H Lochs, G Kleinberger, W Druml

    Leber, Magen, Darm
    |October 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The C/C_₁₃₉₁₀ and G/G_₂₂₀₁₈ Genotypes for Adult-type Hypolactasia are not Associated with Inflammatory Bowel Disease.

    Scandinavian journal of gastroenterology·2017
    Same author

    Impact of diet and nutraceutical supplementation on inflammation in elderly people. Results from the RISTOMED study, an open-label randomized control trial.

    Clinical nutrition (Edinburgh, Scotland)·2015
    Same author

    Increased intestinal permeability in malnourished patients with liver cirrhosis.

    European journal of clinical nutrition·2012
    Same author

    Algorithm for detection of small-bowel metastasis in malignant melanoma of the skin.

    Endoscopy·2011
    Same author

    Cost-effectiveness of a 3-month intervention with oral nutritional supplements in disease-related malnutrition: a randomised controlled pilot study.

    European journal of clinical nutrition·2011
    Same author

    Inadvertent duplicate publication: Severe poisoning with slow release theophylline.

    British medical journal (Clinical research ed.)·2010

    This study investigated renal function in 80 hepatic coma patients, finding significant renal impairment. Prophylactic dopamine and fluid/electrolyte replacement are suggested for managing hepatic coma-related kidney issues.

    Area of Science:

    • Nephrology
    • Hepatology
    • Critical Care Medicine

    Context:

    • Hepatic coma, a severe complication of liver disease, significantly impacts multiple organ systems.
    • Renal dysfunction is a common and serious comorbidity in patients with advanced hepatic failure.
    • Understanding the patterns of renal impairment is crucial for effective patient management.

    Purpose:

    • To evaluate renal function in patients with hepatic coma (stages III-IV).
    • To identify specific renal abnormalities, including reduced creatinine clearance and hyperaldosteronism.
    • To assess the prevalence of overt renal failure across different forms of hepatic coma.

    Summary:

    • Eighty patients with hepatic coma (acute fulminant, chronic, or mixed forms) underwent renal function assessment.

    Related Experiment Videos

  • Measurements included plasma/urine urea, creatinine, electrolytes, creatinine clearance, and urine sodium/potassium ratio.
  • Renal failure was defined as serum creatinine > 3 mg/dl; abnormalities like reduced clearance, hyperaldosteronism, and tubular necrosis were noted across patient groups.

    • Impact:

    • Findings highlight the high incidence of renal dysfunction in hepatic coma, varying by etiology.
    • The study suggests prophylactic use of dopamine and intravenous sodium/water for managing renal complications.
    • This research informs clinical practice regarding the monitoring and treatment of kidney function in liver failure patients.