Sweat gland function in dermatophytosis

Area of Science:

• Dermatology
• Mycology
• Physiology

Background:

• Dermatophytosis is a common superficial fungal infection affecting the skin.
• Sweat gland function can be impacted by various skin conditions.
• Understanding these impacts is crucial for comprehensive patient care.

Purpose of the Study:

• To investigate sweat gland disturbances in patients with dermatophytosis.
• To explore the underlying mechanisms of these observed disturbances.
• To discuss the clinical significance of sweat gland dysfunction in dermatophytosis.

Main Methods:

• Study included 54 cases of dermatophytosis.
• Observed and documented sweat gland malfunctions, including hypohidrosis and hyperhidrosis.
• Examined sweat duct patency and inflammatory processes in the dermis.

Main Results:

• Intense hypohidrosis was the predominant sweat gland disturbance.
• Hyperhidrotic phenomena were noted in specific lesion areas in some cases.
• Sweat duct closure at the keratin level was a significant finding.
• Hypohidrosis was also present in adjacent normal skin areas in over 50% of cases.
• Dermal inflammation was implicated in affecting gland function.

Conclusions:

• Sweat gland disturbances, particularly hypohidrosis, are common in dermatophytosis.
• Mechanisms include sweat duct closure and inflammatory effects on glands.
• These disturbances have clinical relevance to the management of dermatophytosis.