Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Short-latency somatosensory evoked potentials

M Kritchevsky, W C Wiederholt

    Archives of Neurology
    |November 1, 1978
    PubMed
    Summary

    Knee reference recordings are crucial for observing early somatosensory evoked potential (SEP) components during median nerve stimulation. This method helps identify the origin of these important neurological signals.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Neuroepidemiologic research initiatives on Guam: past and present.

    Neuroepidemiology·1999
    Same author

    Discourse deficits following right hemisphere damage in deaf signers.

    Brain and language·1999
    Same author

    Transient global amnesia: a complication of incremental exercise testing.

    Medicine and science in sports and exercise·1998
    Same author

    The association of non-insulin-dependent diabetes mellitus and cognitive function in an older cohort.

    Journal of the American Geriatrics Society·1998
    Same author

    Tau is a candidate gene for chromosome 17 frontotemporal dementia.

    Annals of neurology·1998
    Same author

    Transient global amnesia and functional retrograde amnesia: contrasting examples of episodic memory loss.

    Philosophical transactions of the Royal Society of London. Series B, Biological sciences·1998

    Area of Science:

    • Neuroscience
    • Electrophysiology
    • Clinical Neurology

    Background:

    • Somatosensory evoked potentials (SEPs) are valuable diagnostic tools in neurology.
    • Understanding the origin of short-latency SEP components is essential for accurate clinical interpretation.
    • Previous studies have explored SEP generation, but precise localization of early potentials remains an area of investigation.

    Purpose of the Study:

    • To investigate the origin of short-latency somatosensory evoked potential (SEP) components.
    • To compare the efficacy of different reference electrode placements (ear, forehead, knee) in SEP recording.
    • To identify specific SEP potentials (P10, P12, P14, N19, P20, P23) and their likely neuroanatomical sources.

    Main Methods:

    • Median nerve stimulation was performed in 20 healthy subjects.
    • Somatosensory evoked potentials (SEPs) were recorded using ear, forehead, and knee reference electrodes.
    • Analysis focused on identifying and characterizing short-latency SEP components.

    Main Results:

    • Six distinct short-latency SEP components were identified: P10, P12, P14, N19, P20, and P23.
    • Knee reference recording was found to be superior, enabling visualization of all early potentials.
    • Likely origins were proposed: P10 (brachial plexus), P12 (dorsal column nuclei/medial lemniscus), P14 (thalamus), N19 (sensory radiation/cortex), and P23 (contralateral somatosensory cortex). The origin of P20 remains unclear.

    Conclusions:

    • Knee reference recording is recommended for optimal detection of early SEP components during median nerve stimulation.
    • The study provides insights into the neuroanatomical generators of specific short-latency SEPs.
    • Clinical recommendations include using bilateral median nerve stimulation at 4 Hz with stimulus intensity sufficient to elicit a thumb twitch.

    Related Experiment Videos