Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Familial cavernous angiomas

J M Bicknell, T J Carlow, M Kornfeld

    Archives of Neurology
    |November 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Performance evaluation of a visual simulator for intraocular lenses].

    Die Ophthalmologie·2026
    Same author

    Randomized clinical trial of laparoscopic ultrasonography before laparoscopic colorectal cancer resection.

    The British journal of surgery·2017
    Same author

    Evaluation of robotic assistance in neurosurgical applications.

    Journal of robotic surgery·2016
    Same author

    Triple-deck analysis of transonic high Reynolds number flow through slender channels.

    Philosophical transactions. Series A, Mathematical, physical, and engineering sciences·2014
    Same author

    Neuropathology of chronic GM2 gangliosidosis due to hexosaminidase A deficiency.

    Clinical neuropathology·2008
    Same author

    Risk analysis and safety assessment in surgical robotics: a case study on a biopsy robot.

    Minimally invasive therapy & allied technologies : MITAT : official journal of the Society for Minimally Invasive Therapy·2006
    Same journal

    Incorrect Table Entries and Word.

    Archives of neurology·2016
    Same journal

    IDEAL for CCSVI Research-Reply.

    Archives of neurology·2013
    Same journal

    Atlas of Inherited Metabolic Diseases, 3rd ed.

    Archives of neurology·2013
    Same journal

    Error in byline: in heterogeneity of coenzyme q10 deficiency: patient study and literature review.

    Archives of neurology·2013
    Same journal

    This month in archives of neurology.

    Archives of neurology·2013
    Same journal

    About this journal.

    Archives of neurology·2013
    See all related articles

    Cavernous angiomas, rare CNS vascular malformations, can occur within families. Recognizing this familial link is crucial for timely diagnosis and management of these surgically remediable conditions.

    Area of Science:

    • Neurology
    • Genetics
    • Vascular Malformations

    Background:

    • Cavernous angiomas are uncommon, surgically treatable vascular malformations of the central nervous system (CNS).
    • They can manifest with symptoms such as hemorrhage, seizures, and focal neurological deficits.
    • Previous literature documented three families with cavernous angiomas.

    Observation:

    • This study reports two additional families with a history of cavernous angiomas.
    • The first family presented with a mother's sudden death, a pontine cavernous angioma in one son, pontine signs and a mass in another son, and seizures with a cerebral lesion in the grandson.
    • The second family included a father with an excised caudate cavernous angioma, a daughter with a spinal cord mass, and another daughter with seizures and a temporal lobe vascular lesion.

    Findings:

    Related Experiment Videos

    • The observations suggest a potential hereditary pattern in cavernous angioma development.
    • Multiple affected individuals across generations within the reported families indicate a familial predisposition.
    • The diverse clinical presentations, including hemorrhage, seizures, and focal deficits, highlight the varied impact of these malformations.

    Implications:

    • Increased awareness of familial cavernous angiomas can improve diagnostic rates.
    • Early identification of at-risk family members may facilitate prompt intervention.
    • Understanding the genetic basis of familial cavernous angiomas could lead to targeted therapies.