Related Experiment Videos
Catalytic mechanism of histone in peptide formation from phenylalanyl adenylate
Origins of Life
|December 1, 1982
Abstract:
Catalytic action of histone on peptide formation from phenylalanyl adenylate was studied. A peptide bond formation from phenylalanyl adenylate releases two protons. The proton release was increased in the presence of histone at a higher concentration. The catalytic action seems to be due to basic circumstance induced by histone, since (1) basic condition enhanced the proton release; (2) basic amino acid did not enhance the proton release.