Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A successful peer review program for regulatory decisions

K D Fisher

    Regulatory Toxicology and Pharmacology : RTP
    |December 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Postmortem titin proteolysis is influenced by sarcomere length in bovine muscle.

    Journal of animal science·2011
    Same author

    Comparison of molecular strategies for breast cancer virotherapy using oncolytic adenovirus.

    Human gene therapy·2008
    Same author

    Incorporation of a laminin-derived peptide (SIKVAV) on polymer-modified adenovirus permits tumor-specific targeting via alpha6-integrins.

    Cancer gene therapy·2007
    Same author

    Use of synthetic vectors for neutralising antibody resistant delivery of replicating adenovirus DNA.

    Gene therapy·2006
    Same author

    Extended plasma circulation time and decreased toxicity of polymer-coated adenovirus.

    Gene therapy·2004
    Same author

    Adenovirus retargeting and systemic delivery.

    Ernst Schering Research Foundation workshop·2003
    Same journal

    The NTP Chronic Inhalation Study Does Not Support an Inherent Lung Cancer Hazard of Talc: Implications of Lung Particle Overload and Maximum Tolerated Dose.

    Regulatory toxicology and pharmacology : RTP·2026
    Same journal

    Consideration of Carcinogenicity and Mode of Action Information by an Independent Expert Panel to Support Derivation of No-Significant-Risk-Level Values for Vinyl Acetate Monomer.

    Regulatory toxicology and pharmacology : RTP·2026
    Same journal

    Which carcinogenicity study should I use? Automated identification of reliable studies.

    Regulatory toxicology and pharmacology : RTP·2026
    Same journal

    Adoption of artificial intelligence in drug review across the lifecycle: Transformation of regulatory decision-making.

    Regulatory toxicology and pharmacology : RTP·2026
    Same journal

    Cardiovascular outcomes following intrauterine and lactational exposure to cyantraniliprole in male Wistar rats.

    Regulatory toxicology and pharmacology : RTP·2026
    Same journal

    Pesticide residue and mycotoxin occurrence in apples and their impact on human health in Morocco.

    Regulatory toxicology and pharmacology : RTP·2026
    See all related articles

    A long-standing federal peer review program evaluated over 400 food ingredients for safety. These expert opinions informed the FDA's regulatory actions on Generally Recognized as Safe (GRAS) substances.

    Area of Science:

    • Food Science
    • Toxicology
    • Regulatory Science

    Background:

    • A federal peer review program has provided expert scientific opinions since 1962.
    • This program supports various life science fields and federal agencies.

    Purpose of the Study:

    • To evaluate the safety of Generally Recognized as Safe (GRAS) food ingredients for the U.S. Food and Drug Administration (FDA).
    • To provide expert opinions to inform regulatory decisions on food ingredient safety.

    Main Methods:

    • A Select Committee conducted a 10-year evaluation of over 400 GRAS substances.
    • Evaluative reports were submitted to the FDA for review and public comment.

    Main Results:

    • The FDA utilized these expert reports to inform decisions on the health aspects of food ingredients.

    Related Experiment Videos

  • The comprehensive evaluations contributed to regulatory actions concerning food safety.

    • Conclusions:

    • The peer review program successfully provided critical scientific assessments for regulatory bodies.
    • A forthcoming publication will detail the work of the Select Committee on GRAS substances.