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Auditory brainstem responses in perinatal asphyxia

P Kileny, C Connelly, C Robertson

    International Journal of Pediatric Otorhinolaryngology
    |June 1, 1980
    PubMed
    Summary
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    Auditory brainstem responses (ABR) reveal significant differences in asphyxiated neonates compared to healthy infants. ABR testing shows potential for monitoring recovery from hypoxic encephalopathy in newborns.

    Area of Science:

    • Neuroscience
    • Neonatal Medicine
    • Audiology

    Background:

    • Hypoxic encephalopathy is a major concern in neonates.
    • Auditory brainstem responses (ABR) are a key diagnostic tool for assessing auditory pathway function.
    • Understanding ABR changes in neonates with CNS suppression is crucial for prognosis.

    Observation:

    • ABR were recorded from 14 asphyxiated neonates with CNS suppression and compared to healthy controls.
    • Neonates were matched for gestational age and weight.
    • Unfiltered clicks were used to elicit ABR.

    Findings:

    • Statistically significant differences in ABR parameters were observed between asphyxiated and healthy neonates.
    • Asphyxiated neonates generally exhibited longer ABR component latencies and interwave intervals.

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  • Short-term and 6-month follow-up data indicated ABR sensitivity to recovery from hypoxic encephalopathy.

    • Implications:

    • ABR can serve as a sensitive biomarker for neurological dysfunction and recovery in neonates following asphyxia.
    • These findings support the use of ABR in the clinical management and prognostic assessment of neonatal hypoxic encephalopathy.
    • Further research can refine ABR interpretation for improved patient outcomes.