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Related Experiment Videos

Delayed stroke following carotid occlusion

S Finklestein, G M Kleinman, R Cuneo

    Neurology
    |January 1, 1980
    PubMed
    Summary
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    A patient experienced a fatal stroke due to a carotid artery clot fragment traveling to the brain, despite anticoagulant treatment. This case highlights the risk of embolism from carotid thrombus propagation.

    Area of Science:

    • Neurology
    • Vascular Medicine
    • Pathology

    Background:

    • Cervical internal carotid artery occlusion can lead to ischemic stroke.
    • Anticoagulant therapy is a common treatment to prevent clot formation and propagation.
    • Cerebral infarction remains a significant cause of mortality and morbidity.

    Observation:

    • A 60-year-old patient presented with a lethal hemispheric infarction.
    • The infarction occurred 3 days after documented occlusion of the ipsilateral cervical internal carotid artery.
    • The patient was undergoing anticoagulant therapy at the time of the event.

    Findings:

    • Pathologic examination revealed evidence consistent with embolism.
    • The source of the embolism was identified as the distal "tail" of a propagated carotid thrombus.

    Related Experiment Videos

  • This mechanism explains the patient's fatal stroke.
  • Implications:

    • Embolism from propagated carotid thrombus is a potential cause of stroke, even with anticoagulation.
    • This finding underscores the importance of understanding thrombus dynamics in cerebrovascular disease.
    • Further research may explore advanced imaging or therapeutic strategies to mitigate risks associated with carotid thrombus propagation.