Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Hyperviscosity in the small-for-gestational age infant

D O Hakanson, W Oh

Biology of the Neonate

|January 1, 1980

Summary

Hyperviscosity affects 17.7% of small-for-gestational age infants, often linked to high venous hematocrit. Clinical symptoms show some correlation but lack specificity for this neonatal complication.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

CriteriaMapper: establishing the automatic identification of clinical trial cohorts from electronic health records by matching normalized eligibility criteria and patient clinical characteristics.

Scientific reports·2024

Same author

Neurodevelopmental outcomes of extremely low birth weight infants with spontaneous intestinal perforation or surgical necrotizing enterocolitis.

Journal of perinatology : official journal of the California Perinatal Association·2013

Same author

Whole-blood viscosity in the neonate: effects of gestational age, hematocrit, mean corpuscular volume and umbilical cord milking.

Journal of perinatology : official journal of the California Perinatal Association·2013

Same author

A simple method to fabricate stabilized record bases: a modified approach using casting wax for the borders.

The European journal of prosthodontics and restorative dentistry·2013

Same author

Co-transplantation of third-party umbilical cord blood-derived MSCs promotes engraftment in children undergoing unrelated umbilical cord blood transplantation.

Bone marrow transplantation·2013

Same author

Does aggressive phototherapy increase mortality while decreasing profound impairment among the smallest and sickest newborns?

Journal of perinatology : official journal of the California Perinatal Association·2012

Area of Science:

Neonatalogy
Pediatric Hematology
Perinatology

Background:

Small-for-gestational age (SGA) infants are recognized as being at increased risk for hyperviscosity.
The exact incidence and clinical implications of hyperviscosity in SGA neonates remain unclear.

Purpose of the Study:

To prospectively determine the incidence of hyperviscosity in small-for-gestational age infants.
To investigate the relationship between venous hematocrit, clinical symptoms, and hyperviscosity in this population.

Main Methods:

A prospective survey of 4,974 consecutive livebirths was conducted.
Small-for-gestational age was defined as birth weight below the 10th percentile with malnutrition signs.
Hyperviscosity was defined as venous blood viscosity above 2 standard deviations from the norm, measured via microviscometry.

Main Results:

Out of 79 identified SGA infants, 14 (17.7%) were hyperviscous.
Hyperviscous infants had venous hematocrit ranging from 61-70%, compared to 37-62% in normoviscous infants.
A significant association was found between hyperviscosity and a predefined symptom complex (57% vs. 25%, p < 0.05).

Conclusions:

Hyperviscosity syndrome occurs in approximately 17.7% of small-for-gestational age infants.
Venous hematocrit levels, particularly around 64%, are predictive of hyperviscosity.
While clinical symptoms correlate with hyperviscosity, they lack specificity for diagnosing this neonatal complication.

Related Experiment Videos