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Metastatic prostatic adenocarcinoma to the temporal bone

R J Coppola, V D Salanga

    Neurology
    |March 1, 1980
    PubMed
    Summary

    Prostatic adenocarcinoma rarely metastasizes to the temporal bone, causing multiple cranial nerve palsies and hearing loss. This case highlights a rare presentation of advanced prostate cancer.

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    Area of Science:

    • Oncology
    • Neurology
    • Otolaryngology

    Background:

    • Metastasis of prostatic adenocarcinoma to the temporal bone is exceptionally rare.
    • Prostate cancer typically spreads to bone, lymph nodes, and lungs.

    Observation:

    • A patient presented with paralysis of multiple lower cranial nerves (VII, IX, X, XI, and XII) and oculosympathetic fibers.
    • The patient also exhibited ipsilateral conductive hearing loss.

    Findings:

    • Histologic analysis of a temporal bone biopsy confirmed metastatic adenocarcinoma of prostatic origin.
    • This represents the second reported English literature case and seventh worldwide of prostate cancer metastasis to the temporal bone.

    Implications:

    • This case underscores the importance of considering rare metastatic sites in advanced prostate cancer.
    • Understanding these rare presentations is crucial for accurate diagnosis and comprehensive patient management.
    • Highlights the need for detailed histopathological examination in complex neurological and otological cases.

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