Maternal morbidity due to beta-adrenergic therapy. Pre-existing cardiomyopathy aggravated by fenoterol

In the 32nd wk, fenoterol was administered to a patient during her first pregnancy because of premature rupture of the membranes and uterine contractions after 2 wk of medication. At 8 microgram/min of fenoterol, total irregularity of the maternal pulse occurred. In the 35th wk, cesarean section had to be performed because of fetal asphyxia at 5 cm of cervical dilatation. Intensive care treatment of the mother was necessary during the postoperative phase. The diagnosis of pre-existing congestive cardiomyopathy was made. Non-invasive examination of the heart is advised before beta-adrenergic drugs are given.