Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cerebral embolism in Libman-Sacks endocarditis

I S Fox, A M Spence, R F Wheelis

    Neurology
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Reply to comment on: 'Predicting the efficacy of radiotherapy in individual glioblastoma patients in vivo: a mathematical modeling approach'.

    Physics in medicine and biology·2016
    Same author

    Changes in emotionality following section of the tractus occipito-mesencephalicus in the barbary dove (Streptopelia risoria).

    Behavioural processes·2014
    Same author

    ACUTE PUERPERAL COMPLETE INVERSION OF THE UTERUS: REPLACEMENT: RECOVERY.

    British medical journal·2010
    Same author

    Sulphonamide Therapy for Lupus Erythematosus.

    British medical journal·2010
    Same author

    Fulminating Purpura and Adrenal Haemorrhage.

    British medical journal·2010
    Same author

    Immediate Blood Transfusion in Obstetric Shock.

    British medical journal·2010

    Systemic lupus erythematosus (SLE) can cause strokes due to Libman-Sacks endocarditis. This condition involves vegetations on heart valves leading to brain emboli and infarcts.

    Area of Science:

    • Neurology
    • Cardiology
    • Rheumatology

    Background:

    • Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.
    • Cerebrovascular events are a known complication of SLE, but the underlying mechanisms can be varied.

    Observation:

    • A 57-year-old female patient with SLE presented with left homonymous hemianopia, hemiparesis, left-sided clonic seizures, and declining consciousness.
    • Autopsy revealed multiple cerebral infarcts and arterial emboli.

    Findings:

    • The brain infarcts and emboli were traced to verrucae associated with Libman-Sacks endocarditis.
    • This represents an uncommon embolic pathway for cerebral injury in SLE patients.

    Implications:

    Related Experiment Videos

  • Clinicians and pathologists should consider Libman-Sacks endocarditis as a potential cause of stroke in SLE patients.
  • Recognizing this specific vascular mechanism is crucial for accurate diagnosis and management of neurological complications in SLE.