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[Serum ferritin and iron therapy in childhood. Experiences with iron resin adsorbate (author's transl)]
Insights
This study shows that an iron resin adsorbate effectively treats iron deficiency anemia in children. Daily treatment led to significant increases in hemoglobin and iron reserves.
Area of Science:
- Pediatrics
- Hematology
- Nutritional Science
Background:
- Iron deficiency anemia (IDA) is a common pediatric condition.
- Accurate diagnosis relies on multiple hematological and iron status indicators.
- Effective treatment is crucial for child development.
Purpose of the Study:
- To evaluate the efficacy of an iron resin adsorbate for treating iron deficiency in children.
- To assess the impact on hemoglobin levels and iron reserves.
Main Methods:
- Diagnosis involved analyzing hemoglobin, red cell count, hematocrit, MCH, serum iron, iron binding capacity, iron saturation, and serum ferritin.
- Treatment utilized a daily oral iron resin adsorbate.
- Hemoglobin and serum ferritin levels were monitored over time.
Main Results:
- Average daily hemoglobin increase was 0.71 g/L over five weeks in children with IDA (initial 91 g/L).
- A child with severe anemia (54 g/L) showed a daily increase of 2.57 g/L hemoglobin.
- Serum ferritin levels rose from 13 to 51 microgram/L in 12 weeks, indicating replenished iron stores.
Conclusions:
- Iron resin adsorbate is an effective treatment for pediatric iron deficiency and anemia.
- The treatment successfully restored iron reserves, as evidenced by increased serum ferritin.
- This therapeutic approach offers a viable option for managing iron deficiency in children.
Abstract:
In 40 children with iron deficiency anemia and in 15 children with iron deficiency without anemia the diagnosis is made by hemoglobin, red cell count, hematocrit, MCH, serum iron, iron binding capacity, iron saturation and serum ferritin. For treatment an iron resin adsorbate, given one time daily, was used. The average daily increase of hemoglobin in the time of five weeks is 0,71 g/l by an initial value of 91 g/l. In a child with severe anemia (54 g/l) the daily increase was 2,57 g/l Hemoglobin. Serum ferritin increased in 12 weeks from 13 to 51 microgram/l, this normal value shows the filling of the iron reserves.