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Updated: Aug 10, 2026

Induction of Alloantigen-specific Anergy in Human Peripheral Blood Mononuclear Cells by Alloantigen Stimulation with Co-stimulatory Signal Blockade
Published on: March 14, 2011
Plasmapheresis as an adjunct to management of Rh isoimmunization
Abstract:
Plasmapheresis as therapy for Rh isoimmunization has gained recent attention in Great Britain; however, this technique has not been widely accepted in the United States. At Wilford Hall USAF Medical Center, separator was beneficial in the management of a patient with Rh isoimmunization. A decrease in the delta optical density (OD) 450 followed the onset of plasmapheresis by 3 and 4 weeks and a correlation between the plasma anti-D concentration and the severity of the delta OD 450 was demonstrated.
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