A follow-up of the protein pattern after operations in patients treated with an oral enzyme

The sera of 32 patients have been studied in order to assess the behaviour of the main proteins, which could be identified with a two-dimensional electrophoresis, after operation. 20 of them were given an oral enzyme preparation of trypsin/chymotrypsin (Chymoral 100/F); the others were given no therapy. The analysis was performed comparing the relative concentration of 17 proteins in the pre-operative phase and the fifth day after the operation. Some variations known already and induced by this therapy (like the increase of alpha-1-antitrypsin), have been confirmed, but it has also been demonstrated, in the patients treated with Chymoral, a clear reduction of the constant loss of albumin and pre-albumin, which occurs after an operation.