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[On the uricosuric activity of etofylline clofibrate (author's transl)]
Arzneimittel-Forschung
|January 1, 1980
Abstract:
In a review study including altogether 5 clinical trials with a total of 221 hyperlipidaemic patients the influence of 1-(theophyllin-7-yl)-ethyl-2-[2-(p-chlorophenoxy)-2-methylpropionate] (etofylline clofibrate, Duolip) treatment on serum uric acid level was investigated. 73 patients thereof, i.e., one-third of the hyperlipidaemic patients, had increased values of uric acid. In all studies a statistically significant and clinically relevant uricosuric activity was established.