[Human i.v. immune globulin by chemical modification with beta-propiolactone/radiochemical study (author's transl)]

Elimination of anticomplementary activity of human immune globulin G (IgG, Intraglobin) is achieved by introduction of 6 OH-propionic groups per IgG-molecule. These groups introduced by modification with beta-propiolactone, are equally spread out on the molecule and situated at lysin.