Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Alternaria sinusitis

M A Shugar, W W Montgomery, N E Hyslop

    The Annals of Otology, Rhinology, and Laryngology
    |May 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Alternaria, a fungus, can cause destructive naso-oral disease in healthy individuals, not just allergic reactions or opportunistic infections. This case highlights its potential for invasive granulomatous infections.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Opposition-effect experimentation.

    Optics letters·2009
    Same author

    Manifestations and outcome of extra-pulmonary tuberculosis: impact of human immunodeficiency virus co-infection.

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2005
    Same author

    State-of-the-art for osteoplastic frontal sinus operation.

    Otolaryngologic clinics of North America·2001
    Same author

    Use of the radial forearm fasciocutaneous free flap and montgomery salivary bypass tube for pharyngoesophageal reconstruction.

    Head & neck·2000
    Same author

    Evidence for laryngeal paralysis in cricoarytenoid joint arthritis.

    The Laryngoscope·2000
    Same author

    Montgomery Thyroplasty Implant for vocal fold immobility: phonatory outcomes.

    The Annals of otology, rhinology, and laryngology·2000
    Same journal

    Laryngeal Injuries Following General Endotracheal Anesthesia: A Case Series.

    The Annals of otology, rhinology, and laryngology·2026
    Same journal

    Clinical and Voice Outcome Differences in Vocal Cord Cysts with and Without Sulcus Vocalis: Insights From a Tertiary Center in Saudi Arabia.

    The Annals of otology, rhinology, and laryngology·2026
    Same journal

    Bioabsorbable Stenting in a Case of Severe Pediatric Posterior Glottic Stenosis.

    The Annals of otology, rhinology, and laryngology·2026
    Same journal

    Efficacy and Safety of Finafloxacin Otic Suspension, 0.3% for the Treatment of Acute Otitis Externa: Results from two Phase III Randomized Clinical Studies.

    The Annals of otology, rhinology, and laryngology·2026
    Same journal

    Evaluation Of the Expression Levels Of SerpinB3/B4/B10, Interleukin-17 As Biomarkers For Chronic Rhinosinusitis With Nasal Polyps.

    The Annals of otology, rhinology, and laryngology·2026
    Same journal

    Correlation of Patient-Reported Symptoms With Rhinogram Features Beyond Simple Airway Resistance.

    The Annals of otology, rhinology, and laryngology·2026
    See all related articles

    Area of Science:

    • Mycology
    • Immunology
    • Pathology

    Background:

    • Alternaria fungi are typically considered nonpathogenic contaminants in clinical settings.
    • Hypersensitivity to Alternaria spores is a known cause of allergic pulmonary disease.
    • Recent evidence suggests Alternaria can opportunistically invade immunocompromised individuals.

    Observation:

    • This report details a case of invasive Alternaria infection in an otherwise healthy patient.
    • The fungus was repeatedly isolated from naso-oral tissue specimens.
    • Biopsies revealed granulomatous, hyperplastic, and destructive disease affecting the maxilla, facial soft tissues, ethmoid sinus, and palate.

    Findings:

    • Alternaria species can cause severe, destructive granulomatous disease in immunocompetent hosts.

    Related Experiment Videos

  • The infection presented as a rapidly progressing, fistulizing lesion.
  • Histopathology confirmed fungal invasion and a significant inflammatory response.

    • Implications:

    • This case expands the known clinical spectrum of Alternaria infections.
    • It underscores the importance of considering fungi in destructive inflammatory conditions of the head and neck.
    • Management necessitates a multidisciplinary approach involving otolaryngology, infectious diseases, and pathology.