[Myocardial DNA damage and repair in emotional-painful stress]

[Partial depolymerization of myocardial DNA was found to ensue within the first hours after termination of stress exposure. The depolymerization was accompanied by DNA synthesis repair manifesting both in in-vivo and in-vitro experiments. With time the repair of DNA synthesis decreased while its polymerism got recovered. The data obtained provide evidence in favour of the relationship between the stress-induced free radical activation and damage and subsequent DNA synthesis repair.