[Diagnosis and treatment of a neonatal isoimmuno-thrombocytopenia]

The diagnosis of neonatal isoimmune thrombocytopenia is based upon the exclusion of other causes of thrombocytopenia in the newborn, and on successful treatment by transfusion of compatible, preferably maternal, platelets, If isoimmunization is suspected, detection of antiplatelet isoantibodies should be attempted using specific serological methods. This case report nevertheless illustrates that failure to confirm isoimmunization serologically does not exclude the diagnosis of neonatal isoimmune thrombocytopenia.