[Comparison of two methods for the determination of oestrogens in pregnancy urine (author's transl)]

A method based on the inhibition of hemagglutination for the determination of estriol-16-alpha-glucuronide is compared to the method of Kober and Ittrich. A sufficient degree of correlation (p less than 0.001) is found, when the daily estrogen production (Kober-Ittrich) in the last trimenon is compared to the estriol-concentration in the morning urine, analyzed by the hemagglutination method, which is suitable for the total estrogen determination too. Results below 23 microgram estriol/ml morning urine are pathological. Advantages of this method result from the fact, that no special equipment is required to carry out this fast assay.