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Related Experiment Videos

Riboflavin status during pregnancy

S C Vir, A H Love, W Thompson

    The American Journal of Clinical Nutrition
    |December 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Riboflavin deficiency was identified in pregnant women across trimesters and postpartum. Despite adequate intake, biochemical deficiency was prevalent, though not progressive during pregnancy.

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    Area of Science:

    • Biochemistry
    • Nutritional Science
    • Human Physiology

    Background:

    • Riboflavin (vitamin B2) is crucial for cellular metabolism and energy production.
    • Pregnancy is a period of increased nutritional demand, potentially impacting vitamin status.
    • Assessing riboflavin status is important for maternal and fetal health.

    Purpose of the Study:

    • To determine the riboflavin status in nonpregnant and pregnant women.
    • To investigate the prevalence of riboflavin deficiency during different stages of pregnancy and early postpartum.
    • To explore correlations between riboflavin status, intake, and pregnancy outcomes.

    Main Methods:

    • Erythrocyte glutathione reductase activation test (EGR-ACT) was used to assess riboflavin status.
    • Study included 20 nonpregnant women and 60 pregnant women (2nd trimester, 3rd trimester, early postpartum).

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  • Nutritional intake and other factors (parity, contraceptive use, smoking, alcohol) were also considered.

    • Main Results:

    • Biochemical riboflavin deficiency (EGR-ACT > 1.20) was found in 21.7% of 2nd-trimester, 20.8% of 3rd-trimester, and 29.6% of postpartum women.
    • No nonpregnant subjects showed deficiency.
    • Riboflavin intake was generally adequate, with a negative correlation between intake and deficiency at the 3rd trimester; no progressive deterioration or correlation with pregnancy outcome was observed.

    Conclusions:

    • Biochemical riboflavin deficiency is prevalent in pregnant women and persists into the early postpartum period.
    • Factors like previous pregnancies, oral contraceptive use, smoking, and alcohol did not consistently influence deficiency incidence.
    • Further research may be needed to understand the specific causes and implications of riboflavin deficiency during pregnancy.