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A prospective study of lacunar infarction using computerized tomography

G A Donnan, B M Tress, P F Bladin

    Neurology
    |January 1, 1982
    PubMed
    Summary

    Computed tomography (CT) scans can detect lacunar infarction in stroke patients. A negative CT scan does not guarantee a better prognosis, but repeated hemiplegia bursts may indicate a positive scan.

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    Area of Science:

    • Neurology
    • Radiology
    • Medical Imaging

    Background:

    • Lacunar infarction is a common type of stroke.
    • Early detection and prognosis of lacunar infarction are crucial for patient management.
    • Computed tomography (CT) is a primary imaging modality for stroke evaluation.

    Purpose of the Study:

    • To evaluate the utility of sequential CT scans in diagnosing lacunar infarction.
    • To correlate clinical features with CT findings in patients with suspected lacunar infarction.
    • To assess the prognostic value of CT scan results in stroke patients.

    Main Methods:

    • Sequential CT scans were performed on patients with clinical suspicion of lacunar infarction or ischemia.
    • Clinical features were recorded and correlated with imaging findings.

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  • Statistical analysis was used to determine the significance of observed correlations.

    • Main Results:

    • Sixty-nine percent of patients presented with confirmed lacunar infarction on CT.
    • A negative CT scan did not correlate with a better prognosis.
    • Patients experiencing repeated hemiplegic episodes (capsular warning syndrome) showed a higher likelihood of CT-positive results (p < 0.01).
    • Partial stroke syndromes, such as isolated monoparesis or dysarthria, were observed in 32% of cases.

    Conclusions:

    • Sequential CT scanning is valuable in diagnosing lacunar infarction.
    • CT findings should be interpreted alongside clinical presentation for accurate prognosis.
    • Capsular warning syndrome is a significant clinical predictor of positive CT findings in lacunar infarction.