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Related Experiment Videos

Primary writing tremor: a selective action tremor

H L Klawans, R Glantz, C M Tanner

    Neurology
    |February 1, 1982
    PubMed
    Summary

    This study describes a tremor disorder affecting handwriting in six patients, appearing between ages 8 and 54. The tremors responded to anticholinergic agents but not propranolol HCl, distinguishing it from essential tremor.

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    Area of Science:

    • Neurology
    • Movement Disorders
    • Clinical Neuroscience

    Background:

    • Essential tremor is a common movement disorder characterized by action tremor.
    • Differentiating tremors is crucial for accurate diagnosis and treatment.

    Observation:

    • Six patients presented with progressive handwriting difficulties due to jerking movements.
    • Tremors were precipitated by writing and specific muscle activities, with no rest tremor observed.
    • Three patients had mild postural tremor.

    Findings:

    • The tremor was elicited by specific muscle activities like wrist pronation or finger abduction, persisting with maintained posture.
    • No family history of tremors was reported; two patients had a history suggestive of birth hypoxia.
    • The condition did not respond to propranolol HCl but showed improvement with centrally acting anticholinergic agents.

    Implications:

    • This tremor presentation appears distinct from benign essential tremor.
    • Centrally acting anticholinergic agents may be a viable treatment option for this specific tremor type.
    • Further research is warranted to understand the pathophysiology and long-term prognosis of this tremor disorder.

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