Angiosarcomas of the uterus and ovary: clinicopathologic report

The clinicopathologic features of angiosarcomas of the uterus and ovary are described. Extensive review of world literature shows only eight reported cases of angiosarcoma arising in the uterus and two in the ovary. Clinically, both patients presented with nonspecific symptoms. The tumors were found at surgery, and confirmed as angiosarcomas on histologic examination. The ultrastructure of both tumors is also presented. The association with mucinous cystadenoma in the second tumor raises the possibility that this may be a mixed Mullerian tumor. Both tumors behaved in an aggressive fashion.