Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Haemodynamic variables during repeated exercise in chronic lung disease

F Schrijen, V Jezek

    Clinical Science and Molecular Medicine
    |November 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Total hip replacement in patients with ankylosing spondylitis.].

    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca·2010
    Same author

    Interpretation of high wedge pressure on exercise in patients with chronic obstructive pulmonary disease.

    Cardiology·2001
    Same author

    Role of NO pathway, calcium and potassium channels in the peripheral pulmonary vascular tone in dogs.

    The European respiratory journal·2001
    Same author

    alpha(1)-adrenoreceptors and pulmonary hypertension.

    Chest·2000
    Same author

    Pulmonary arterial morphology and intravascular pressure revisited.

    European heart journal·1998
    Same author

    Thrombolysis in acute pulmonary embolism: to whom, how much and how?

    European heart journal·1997

    Repeated exercise in chronic lung disease patients revealed lower pulmonary pressures during the second exercise bout. Systemic arterial pressure changes varied based on oxygen desaturation and perfusion defects.

    Area of Science:

    • Cardiopulmonary Physiology
    • Exercise Physiology

    Background:

    • Chronic lung disease (CLD) impacts cardiopulmonary function during exertion.
    • Understanding hemodynamic responses to repeated exercise is crucial for managing CLD patients.

    Purpose of the Study:

    • To investigate pulmonary and systemic hemodynamics during repeated moderate exercise in patients with CLD.
    • To identify differences in hemodynamic responses between initial and subsequent exercise periods.

    Main Methods:

    • Twenty-eight CLD patients (16 with chronic bronchitis) underwent repeated moderate exercise with a 20-minute rest.
    • Measurements included ventilatory variables, blood gases, cardiac output, and vascular pressures (right ventricular end-diastolic, pulmonary arterial, wedge, systemic arterial).

    Main Results:

    Related Experiment Videos

    • Ventilation and blood gases remained consistent across exercise bouts.
    • Oxygen consumption and hydrogen ion concentration showed slight differences between exercise periods.
    • Pulmonary arterial and wedge pressures decreased during the second rest and exercise; right ventricular filling pressure was lower at rest.
    • Systemic arterial pressure was lower during the second exercise.
    • Cardiac output and pulmonary vascular resistance were unchanged.
    • Systemic arterial pressure changes differed significantly in patients with arterial oxygen desaturation or perfusion defects.

    Conclusions:

    • Repeated exercise in CLD patients leads to adaptive hemodynamic changes, including reduced pulmonary pressures.
    • Individual patient factors like oxygen desaturation influence systemic arterial pressure response during exercise.