Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Biological interaction of selenium with other trace elements in chicks

G O Howell, C H Hill

    Environmental Health Perspectives
    |August 1, 1978
    PubMed
    Summary

    Elements like arsenic, tellurium, tin, and lead can reverse selenium toxicity in chicks. This protection occurred without reducing liver selenium levels, except when high arsenic concentrations were used.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The interaction of iron and ascorbic acid with lead in the chick.

    Biological trace element research·2013
    Same author

    Studies on the role of iron in the reversal of vanadium toxicity in chicks.

    Biological trace element research·2013
    Same author

    Response of hepatic metallothionein to iron administration : Lack of correlation with serum corticosterone.

    Biological trace element research·2013
    Same author

    Poisoning by Linimentum Aconiti: Recovery.

    British medical journal·2010
    Same author

    Preliminary note on the successful breeding of an intermediate host of the Asiatic blood fluke.

    Proceedings of the Helminthological Society of Washington·2010
    Same author

    The chemistry of biological processes. Editorial overview.

    Current opinion in drug discovery & development·2009

    Area of Science:

    • Toxicology
    • Environmental Health
    • Animal Nutrition

    Background:

    • Selenium is an essential trace element but can be toxic at higher concentrations.
    • Understanding factors that mitigate selenium toxicity is crucial for animal health and agriculture.
    • Elements with similar valence electron shells to selenium were investigated for their potential to counteract its toxicity.

    Purpose of the Study:

    • To investigate if elements with similar valence electron shells to selenium could reverse selenium-induced toxicity in chicks.
    • To assess the impact of arsenic, tellurium, tin, and lead on selenium toxicity.

    Main Methods:

    • Chicks were fed a diet containing 25 ppm selenium.
    • Arsenic, tellurium, tin, and lead were added to the diet to evaluate their protective effects.
    • Weight gain was used as the primary indicator of toxicity reversal.
    • Liver selenium concentrations were measured to determine the mechanism of protection.

    Main Results:

    • Arsenic, tellurium, tin, and lead each reversed selenium toxicity in chicks, as indicated by improved weight gain.
    • No significant decrease in liver selenium concentration was observed with these elements, except at high arsenic levels.
    • High levels of arsenic, exceeding those needed for toxicity reversal, did reduce liver selenium concentration.

    Conclusions:

    • Elements with similar valence electron shells to selenium can effectively mitigate selenium toxicity in avian species.
    • The protective mechanism appears to be independent of altering liver selenium accumulation, except possibly with arsenic.
    • Further research into the specific interactions between these elements and selenium metabolism is warranted.

    Related Experiment Videos