Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Metabolic interactions between metals and metalloids

O A Levander

    Environmental Health Perspectives
    |August 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Essential nutrient deficiencies, like calcium and iron, can worsen heavy metal toxicity in animals. This suggests multiple nutritional gaps may impact human health when exposed to pollutants like lead, cadmium, and mercury.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Effect of physical restraint on oxidative stress in mice fed a selenium and vitamin E deficient diet.

    Biological trace element research·2006
    Same author

    Effect of gold(I) compounds on the virulence of an amyocarditic strain of coxsackievirus B3.

    Biological trace element research·2002
    Same author

    Mortality in mice infected with an amyocarditic coxsackievirus and given a subacute dose of mercuric chloride.

    Journal of toxicology and environmental health. Part A·2001
    Same author

    Host nutritional selenium status as a driving force for influenza virus mutations.

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2001
    Same author

    Host selenium status selectively influences susceptibility to experimental viral myocarditis.

    Biological trace element research·2001
    Same author

    Selenium deficiency increases the pathology of an influenza virus infection.

    FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2001
    Same journal

    A New Start.

    Environmental health perspectives·2026
    Same journal

    Time-Varying Exposure to Element Mixtures and Children's Cognition at 5 Years of Age: Findings from the New Hampshire Birth Cohort Study.

    Environmental health perspectives·2026
    Same journal

    Effect of Household Air Pollution on the Gut Microbiome and Virome of Adult Women Living in Uganda.

    Environmental health perspectives·2026
    Same journal

    Comparison of Temperature-Mortality Associations across the Middle East Using Different Exposure Estimation Approaches.

    Environmental health perspectives·2026
    Same journal

    Workflow for Statistical Analysis of Environmental Mixtures.

    Environmental health perspectives·2026
    Same journal

    Effects of Extreme Heat Exposure on Heatstroke and Liver Injury in Mice: The Role of PPARα.

    Environmental health perspectives·2026
    See all related articles

    Area of Science:

    • Environmental Toxicology
    • Nutritional Science
    • Biochemistry

    Background:

    • Heavy metal pollutants (lead, cadmium, mercury) pose significant health risks.
    • Essential nutrients play crucial roles in mitigating toxicant effects.
    • Nutritional deficiencies are common globally, potentially interacting with environmental exposures.

    Purpose of the Study:

    • To review experimental evidence on nutrient deficiencies affecting heavy metal toxicity.
    • To present a theoretical model for multiple nutritional deficiencies and heavy metal toxicity.
    • To explore the implications for human health and environmental pollutant exposure.

    Main Methods:

    • Literature review of animal studies on lead, cadmium, and mercury toxicity.
    • Development of a theoretical model illustrating nutrient-toxin interactions.

    Related Experiment Videos

  • Analysis of potential impacts of marginal nutritional deficiencies on human health.

    • Main Results:

    • Experimental data show deficiencies in calcium, iron, zinc, and selenium can increase heavy metal toxicity in animals.
    • A theoretical model suggests combined nutrient deficiencies may exacerbate heavy metal toxicity.
    • Marginal nutritional deficiencies could be a key factor in human susceptibility to heavy metal pollutants.

    Conclusions:

    • Nutrient status significantly influences the toxicological outcomes of heavy metal exposure.
    • Multiple marginal nutritional deficiencies represent a critical, underappreciated factor in heavy metal toxicity.
    • Understanding these interactions is vital for public health strategies addressing environmental pollution.