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Updated: Aug 14, 2026

5/6th Nephrectomy in Combination with High Salt Diet and Nitric Oxide Synthase Inhibition to Induce Chronic Kidney Disease in the Lewis Rat
Published on: July 3, 2013
Glucose-6-phosphatase dehydrogenase activity in rat urine. Changes following kidney damage (short report)
Abstract:
In rat urine, G-6-PDH activity is regularly present. Following the administration of nephrotoxic substances (D-serine, tetrathionate), or after elicitation of vascular shock (hypoxic kidney damage), a statistically significant increase in urinary G-6-PDH activity occurs. The alterations in urinary G-6-PDH activity largely correspond to the changes in urinary AP activity which, in this study, was determined in all of the experiments.
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