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Vitamin B6 status during pregnancy

S C Vir, A H Love, W Thompson

    International Journal for Vitamin and Nutrition Research. Internationale Zeitschrift Fur Vitamin- Und Ernahrungsforschung. Journal International De Vitaminologie Et De Nutrition
    |January 1, 1980
    PubMed
    Summary

    Vitamin B6 deficiency is common in pregnant women, affecting over 44% during pregnancy and postpartum. Low vitamin B6 intake was prevalent, but not linked to pregnancy outcomes.

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    Area of Science:

    • Nutritional Science
    • Biochemistry
    • Maternal Health

    Background:

    • Vitamin B6 is crucial for numerous metabolic processes.
    • Assessing vitamin B6 status is important, especially during pregnancy.
    • Erythrocyte glutamic-pyruvic transaminase (EGPT) index is a biochemical marker for vitamin B6 status.

    Purpose of the Study:

    • To investigate the nutritional status of vitamin B6 in non-pregnant and pregnant women.
    • To determine the prevalence of vitamin B6 deficiency across different stages of pregnancy and postpartum.
    • To explore the relationship between vitamin B6 status, intake, and pregnancy outcomes.

    Main Methods:

    • Investigated vitamin B6 nutritional status using the erythrocyte glutamic-pyruvic transaminase (EGPT) index.
    • Included 20 non-pregnant women and 60 pregnant women (second trimester, third trimester, and postpartum).
    • Assessed vitamin B6 intake and correlated it with biochemical parameters and pregnancy outcomes.

    Main Results:

    • Vitamin B6 deficiency (EGPT index > 1.15) was observed in 30% of non-pregnant women and 44.4-53.1% of pregnant women.
    • Deficiency occurred across all studied stages of pregnancy and postpartum.
    • Mean vitamin B6 intake was below recommended levels, with only 5.9% meeting the 2.5 mg/day recommendation.
    • No significant correlation was found between vitamin B6 status and intake, or between vitamin B6 status and pregnancy/neonatal outcomes.

    Conclusions:

    • Vitamin B6 deficiency is prevalent in pregnant women and persists postpartum.
    • Inadequate vitamin B6 intake is common, but biochemical markers did not correlate with intake or pregnancy outcomes.
    • Further research may be needed to understand the implications of vitamin B6 status during pregnancy.

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