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Updated: Aug 9, 2026

A New Method for Inducing a Depression-Like Behavior in Rats
Published on: February 22, 2018
Relation between loneliness and depression: a structural equation analysis
Abstract:
Research on loneliness has been hampered by its strong association with depression. The two states frequently co-occur, and measures of the two states are substantially correlated. Inability to manipulate experimentally loneliness or depression makes it difficult to untangle the causal influence of one on the other. The combination of longitudinal design and structural equation methodology is proposed as a solution to this general problem. Measures of loneliness and depression were administered to undergraduates at two points 5 weeks apart. Data from 333 subjects were correlated and analyzed under a succession of structural equation models. Results indicated that loneliness and depression were correlated but clearly different constructs; neither was a direct cause of the other, though both probably share some common origins; both were highly stable over to 5-week-period.
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