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The primary megacystis syndrome

R B Koefoot, G D Webster, E E Anderson

    The Journal of Urology
    |February 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

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    Primary megacystis syndrome is non-obstructive and non-neurogenic, likely stemming from learned dysfunctional voiding. Treatment focuses on correcting vesicoureteral reflux and retraining voiding habits.

    Area of Science:

    • Pediatric Urology
    • Behavioral Medicine

    Background:

    • Primary megacystis syndrome is a rare condition characterized by a large bladder.
    • Its etiology is often unclear, with obstructive and neurogenic causes being investigated.

    Purpose of the Study:

    • To investigate the underlying cause of primary megacystis syndrome in 7 pediatric cases.
    • To determine if the condition is non-obstructive and non-neurogenic.
    • To explore the potential psychogenic origin related to voiding dysfunction.

    Main Methods:

    • Case series review of 7 patients diagnosed with primary megacystis syndrome.
    • Clinical evaluation to rule out obstructive and neurogenic causes.
    • Assessment of voiding habits and associated complications like vesicoureteral reflux.

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    Main Results:

    • The study identified primary megacystis syndrome as non-obstructive and non-neurogenic in all 7 cases.
    • Learned dysfunctional voiding was proposed as the probable psychogenic origin.
    • Vesicoureteral reflux was the major complication identified.

    Conclusions:

    • Primary megacystis syndrome is likely psychogenic, resulting from learned dysfunctional voiding.
    • Initial management should prioritize correcting vesicoureteral reflux.
    • Long-term follow-up and voiding retraining are crucial, with pharmacologic or biofeedback interventions for persistent functional abnormalities.