Related Experiment Video

Updated: Aug 18, 2026

Methods for Acute and Subacute Murine Hindlimb Ischemia
07:57

Methods for Acute and Subacute Murine Hindlimb Ischemia

Published on: June 21, 2016

[Clinical variants of chronic ischemic syndrome of the lower extremities]

A V Serkina, B V Taevskiĭ, V F Negreĭ

    Kardiologiia
    |December 1, 1980
    PubMed

    Insights

    This study analyzed 1,014 cases of lower limb ischemia due to arterial occlusion. "Segmental thromboarteritis" was identified as a distinct condition with poor surgical outcomes.

    Area of Science:

    • Vascular Surgery
    • Arterial Diseases
    • Clinical Angiography

    Context:

    • Chronic ischemic syndrome of the lower limbs affects numerous patients.
    • Occlusive lesions of the aorta bifurcation and iliofemoral segment are common causes.
    • Atherosclerosis is the primary etiology in most cases.

    Purpose:

    • To analyze 1,014 cases of lower limb arterial occlusion.
    • To identify and characterize a distinct form of arterial occlusion, termed "segmental thromboarteritis".
    • To evaluate the outcomes of reconstructive surgery for this specific condition.

    Summary:

    • Analysis of 1,014 patients revealed atherosclerosis as the main cause (95.5%) of aortic bifurcation and iliofemoral occlusive lesions.
    • A distinct group of 20 patients presented with "segmental thromboarteritis", characterized by selective femoral segment lesions.
    • Reconstructive surgery outcomes for "segmental thromboarteritis" were largely unfavorable.

    Impact:

    • Highlights the importance of differentiating "segmental thromboarteritis" from other arterial occlusive diseases.
    • Suggests caution and potentially alternative treatment strategies for "segmental thromboarteritis".
    • Informs surgical decision-making and patient counseling for complex lower limb ischemia.

    More Related Videos

    High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model08:16

    High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

    Published on: March 16, 2022

    Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane08:05

    Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

    Published on: December 9, 2022

    Related Concept Videos

    Assessment of the Cardiovascular System III: Palpation01:27

    Assessment of the Cardiovascular System III: Palpation

    Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
    Jugular Venous Pressure (JVP) Measurement
    Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...
    Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

    Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

    Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
    Peripheral Artery Disease I: Introduction01:30

    Peripheral Artery Disease I: Introduction

    Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
    Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

    Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

    Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
    Peripheral Artery Disease III: Interprofessional Care01:27

    Peripheral Artery Disease III: Interprofessional Care

    Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
    Ischemic Stroke l: Introduction01:15

    Ischemic Stroke l: Introduction

    Ischemic stroke is an acute cerebrovascular condition in which blood flow to a brain region is suddenly interrupted, leading to tissue infarction. Neurons depend on continuous oxygen and glucose supply, so even brief reductions in perfusion cause energy failure, ionic imbalance, and irreversible injury. Ischemic strokes are classified into thrombotic and embolic types based on their underlying mechanisms.Thrombotic MechanismsThrombotic stroke develops when a clot forms within a cerebral artery.