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Related Experiment Videos

The Björk-Shiley valve: intermediate-term follow-up

R B Karp, R J Cyrus, E H Blackstone

    The Journal of Thoracic and Cardiovascular Surgery
    |April 1, 1981
    PubMed
    Summary

    The Björk-Shiley valve shows durability and effectiveness in valve replacement surgery. However, patient factors significantly impact long-term survival, alongside risks of thromboembolism and valve thrombosis.

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    Area of Science:

    • Cardiovascular Surgery
    • Biomaterials Science
    • Clinical Outcomes Research

    Background:

    • The Björk-Shiley mechanical valve has been used for decades in aortic and mitral valve replacement.
    • Understanding long-term outcomes and associated risk factors is crucial for patient management.

    Purpose of the Study:

    • To evaluate the intermediate-term survival and complication rates of the Björk-Shiley prosthesis.
    • To identify factors influencing late survival after aortic, mitral, or double valve replacement.

    Main Methods:

    • A cohort of 643 patients undergoing Björk-Shiley valve replacement was followed for 1-72 months (median 38 months).
    • Survival rates, thromboembolism, valve thrombosis, and functional class improvement were analyzed.
    • Multivariate analysis identified factors associated with late survival.

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    Main Results:

    • Intermediate-term survival was comparable to other prosthetic devices.
    • Patient-related factors (previous valve surgery, race, functional class) and perioperative events significantly impacted survival.
    • Freedom from thromboembolism was favorable, but valve thrombosis occurred in 15 patients, causing 13 deaths.
    • Most patients showed improvement in New York Heart Association (NYHA) functional class.

    Conclusions:

    • The Björk-Shiley valve is durable and effective for valve replacement.
    • Thromboembolism and thrombosis remain significant concerns, necessitating careful patient selection and monitoring.
    • Non-device patient characteristics are critical determinants of long-term survival after valve replacement.