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Recurrent traumatic hyphema due to increased local fibrinolysis
Summary
A traumatic eye injury caused recurrent hyphema, a bleeding condition. Treatment with epsilon-aminocaproic acid resolved the hyphema and normalized abnormal blood clot breakdown times.
Area of Science:
- Ophthalmology
- Hematology
- Trauma Care
Background:
- Eye injuries can lead to significant complications, including hyphema.
- Recurrent hyphema poses a risk for vision loss and requires effective management.
- Coagulation and fibrinolysis play crucial roles in managing bleeding disorders.
Observation:
- A 20-year-old male sustained a right eye contusion injury from a carbonated beverage bottle stopper.
- The patient experienced a recurrent hyphema lasting approximately 6 weeks.
- Laboratory investigations revealed a shortened plasma euglobulin clot lysis time (1.5 hours).
Findings:
- Epsilon-aminocaproic acid treatment effectively resolved the recurrent hyphema.
- The same treatment normalized the shortened plasma euglobulin clot lysis time (from 1.5 h to 4-5 h).
- This suggests a potential link between fibrinolysis and recurrent hyphema in this case.
Implications:
- Epsilon-aminocaproic acid may be a valuable therapeutic option for managing recurrent hyphema post-eye injury.
- Understanding the role of fibrinolysis in traumatic hyphema can guide future treatment strategies.
- This case highlights the importance of comprehensive laboratory evaluation in patients with persistent hyphema.