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Sulphonamide as hemolysis-promoting factor in uremia
Scandinavian Journal of Urology and Nephrology
|January 1, 1980
Abstract:
Nine out of 39 uremic patients treated with sulphonamides because of urinary tract infection developed hemolysis. Heinz-bodies were seen in all cases. In uremic patients a defect of the HMP metabolic pathway renders these patients susceptible to hemolysis when treated with oxidant drugs.