Tuberculosis and minimal change nephrotic syndrome in Lucknow, India

Thirty-six patients with minimal-change nephrotic syndrome (MCNS) were investigated for evidence of tuberculosis. Twenty-three of them were found to be suffering from primary tuberculosis (group A), while the remaining 13 children (non-tuberculous) were grouped as B. Patients were either treated with antituberculous drugs (ATT) and steroids or with steroids alone. Recurrences of MCNS were either absent or few in subgroup Aq1 (ATT and steroids); most recurrences occurred in other subgroups Aw (steroids only), Bq) ATT and steroids) and Bw (steroids along). The possible relationship between the tuberculous infection and MCNS is discussed.