[Radiation block of mitoses and the action of stimulating factors]
Abstract:
Using the HeLa cell culture, the dynamics of the appearance of the mitotic block after irradiation with 600 rads has been studied, in addition to the influence of some proliferating stimulatory factors on this process. It has been shown that in the early periods after irradiation with 600 rads, on the background of the developing G2--M block, the low dose irradiation (20 rads), changes to the medium, and high temperature (41--42 degrees C) effects lead to the increase in the number of mitoses. It is supposed that this increase in the mitotic activity may be due to a heterogeneity of cell populations as to their velocity of passing through the G2-phase.
More Related Videos
08:13Rapid Quantification of Mitogen-induced Blastogenesis in T Lymphocytes for Identifying Immunomodulatory Drugs
Published on: December 27, 2016
11:00Photostimulation by Femtosecond Laser Activates Extracellular-signal-regulated Kinase (ERK) Signaling or Mitochondrial Events in Target Cells
Published on: July 6, 2019
Related Concept Videos
DNA Damage can Stall the Cell Cycle
Mitogens and the Cell Cycle
Abnormal Proliferation
DNA Damage Can Stall the Cell Cycle
Mitogens and the Cell Cycle
Molecular Factors Affecting Cell Division
Several proteins function as internal regulators to ensure each cell cycle stage is completed faithfully before proceeding to the next. Regulator molecules may act directly or influence the activity or production of other...
