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[Lethal courses of gas gangrene infections in autopsy cases (author's transl)]
Zentralblatt Fur Allgemeine Pathologie U. Pathologische Anatomie
|January 1, 1980
Abstract:
15 cases of lethal gas gangrene infections were found in 15,024 autopsies from 1970 to 1975. The infection mode via gastro-intestinal tract is very likely in two thirds of the cases. In particular tumor diseases of intestine are able to yield these base for gas gangrene infection by infiltration of the muscular system in the abdomen.
Insights
Gas gangrene infections are rare but lethal, with gastrointestinal tract involvement being a common cause. Intestinal tumors significantly increase the risk of abdominal gas gangrene due to muscle infiltration.
Area of Science:
- Medical Microbiology
- Pathology
- Gastroenterology
Context:
- A retrospective autopsy study examining lethal gas gangrene cases.
- Data collected from 15,024 autopsies performed between 1970 and 1975.
- Focus on identifying infection pathways and predisposing factors.
Purpose:
- To determine the incidence of lethal gas gangrene in autopsy cases.
- To investigate the primary routes of infection for gas gangrene.
- To identify specific conditions, such as intestinal tumors, that predispose individuals to this infection.
Summary:
- Fifteen cases of lethal gas gangrene were identified out of 15,024 autopsies.
- The gastrointestinal tract was implicated as the likely source of infection in approximately two-thirds of cases.
- Intestinal tumors were found to be a significant predisposing factor, facilitating infection through abdominal muscle infiltration.
Impact:
- Highlights the critical role of the gastrointestinal tract in gas gangrene pathogenesis.
- Underscores the increased risk of gas gangrene associated with intestinal malignancies.
- Informs clinical awareness and diagnostic considerations for gas gangrene, particularly in patients with gastrointestinal pathology.