[Atypical hyperplasia of endometrium -- prognostic trends and therapy (author's transl)]

Atypical hyperplasia of the endometrium was histologically diagnosed in 111 cases at the Gynaecological Hospital of the Medical Academy of Magdeburg, between 1970 and 1976. The cases were defined by three degrees of severity. The need for group differentiation and appropriate therapeutic consequences was established by means of follow-up checks of the above cases. Progressing courses were recorded from 6.9 per cent of the cases in Group I, 13.95 per cent in Group II, and 24.0 per cent in Group III. Hysterectomy was recommended for all persistent and progressing findings in Groups II and III, while long-term supervision was found to be necessary in cases of regression. Sexually mature women with atypical hyperplasia should receive gestagens, between the 16th and 24th days following menstruation, before diagnostic abrasion is applied.