An experimental model of hyperlipemia

Rats were given two kinds of diet: fat-rich (coconut oil, cholesterol, cholic acid) and fat-carbohydrate diet (coconut oil, margarine, cholesterol, wheat flour) for a period of 18 weeks. In the blood serum the triglyceride-cholesterol level and the electrophoretic pattern of lipoproteins were determined. Experimental models of experimental hyperlipemia adequate to type IIb and IV according to Fredrickson were obtained.